ADVANCING HIGH-THROUGHPUT ANTI-HCV DRUG SCREENING: A NOVEL DUAL-REPORTER HCV REPLICON MODEL WITH REAL-TIME MONITORING

Advancing high-throughput anti-HCV drug screening: a novel dual-reporter HCV replicon model with real-time monitoring

Background and purpose: Hepatitis C virus (HCV) infection is a global health concern due to its substantial impact on morbidity and mortality.The burden of diseases related to HCV continues to escalate, particularly as infections progress to late-stage liver conditions, resulting in hepatocellular carcinoma on a global scale.Direct-acting antiviral

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Hidden in the dark under umbrellas: two new Psilolechia species (lichenized Ascomycota , Lecanorales ) described from the Czech Republic

Recent lichenological fieldwork in the Czech Republic resulted in the discovery of two previously unrecognized entities in the genus Psilolechia which are described below as new species: the saxicolous P.cretacea and the lignicolous P.torii.Both taxa regularly Dinner Plate produce a hyphomycetous anamorph in the form of erect, elongate conidiogenou

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Prenatal diagnosis of harlequin ichthyosis: a case report

Harlequin ichthyosis (HI) is a rare and severe form of ichthyosis and is characterized by thickened, hard, armor-like plates of skin that cover the entire body.This disease is caused by mutations in the adenosine Cleaners triphosphate-binding cassette transporter protein A12 gene, and the pattern of inheritance is autosomal recessive.Prenatal sonog

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